What Is Recurrent Major Depressive Disorder?
According to the World Health Organization, major depressive disorder is the world’s leading cause of disability. If clinical remission is not attained and sustained, episodes tend to recur with greater severity and with lessening responsivity to conventional treatments. This is called a recurrent major depressive disorder.


What Is Major Depressive Disorder
?
You may hear this type of depression is referred to as “major depressive disorder”, “clinical depression”, “classic depression” or “MDD”. You might have this type if you feel depressed most of the time for most days of the week.
Like many mental health conditions, it is not always about what’s happening around the person. You can have a loving family, friends, and a dream job. You can have the kind of life that others envy and…. still have a major depressive disorder. Major depression is a severe form of depression that causes symptoms such as:
- sadness, gloom, or grief
- difficulty sleeping or sleeping too much
- lack of energy and fatigue
- changes in appetite
- unexplained aches and pains
- loss of interest in formerly pleasurable activities
- lack of concentration, memory problems, and inability to make decisions
- feelings of worthlessness or hopelessness
- constant worry and anxiety
- thoughts of death, self-harm, or suicide
These symptoms can last weeks or months.
Major Depressive Disorder Vs Depression?
All of us feel sad sometimes. While we may casually use the term “depressed” to describe the moment when they are sad, there is a difference between sadness and depression. Someone with depression may feel sad, guilty, or hopeless, but not really understand why—and the feeling can linger for weeks or even months. If you are struggling with constant sadness or hopelessness, it’s important to understand what depression is, what causes it, and what you can do to manage it. Major Depressive Disorder (MDD) or Clinical depression is the more severe form of depression. It isn’t the same as depression caused by a loss, such as the death of a loved one, or a medical condition, such as a thyroid disorder.
Recurrent Major Depressive Disorder ICD-10
According to ICD-10: “A recurrent major depressive disorder characterized by repeated episodes of depression as described for the depressive episode, without any history of independent episodes of mood elevation and increased energy (mania). There may, however, be brief episodes of mild mood elevation and overactivity (hypomania) immediately after a depressive episode, sometimes precipitated by antidepressant treatment. The more severe forms of recurrent depressive disorder have much in common with earlier concepts such as manic-depressive depression, melancholia, vital depression, and endogenous depression. The first episode may occur at any age from childhood to old age, the onset may be either acute or insidious, and the duration varies from a few weeks to many months. The risk that a patient with the recurrent depressive disorder will have an episode of mania never disappears completely, however many depressive episodes have been experienced. If such an episode does occur, the diagnosis should be changed to bipolar affective disorder.”
Recurrent Major Depressive Disorder ICD-10: Mild, Moderate, Severe, Psychotic.According to ICD-10:
Recurrent depressive disorder
A disorder characterized by repeated episodes of depression as described for depressive episode (F32.-), without any history of independent episodes of mood elevation and increased energy (mania). There may, however, be brief episodes of mild mood elevation and overactivity (hypomania) immediately after a depressive episode, sometimes precipitated by antidepressant treatment. The more severe forms of recurrent depressive disorder (F33.2 and F33.3) have much in common with earlier concepts such as manic-depressive depression, melancholia, vital depression, and endogenous depression. The first episode may occur at any age from childhood to old age, the onset may be either acute or insidious, and the duration varies from a few weeks to many months. The risk that a patient with the recurrent depressive disorder will have an episode of mania never disappears completely, however many depressive episodes have been experienced. If such an episode does occur, the diagnosis should be changed to bipolar affective disorder (F31.-).Incl.:recurrent episodes of:
- depressive reaction
- psychogenic depression
- reactive depression
seasonal depressive disorderExcl.:recurrent brief depressive episodes (F38.1)
F33.0Recurrent depressive disorder, current episode mild
A disorder characterized by repeated episodes of depression, the current episode is mild, as in F32.0, and without any history of mania.
F33.1Recurrent depressive disorder, current episode moderate
A disorder characterized by repeated episodes of depression, the current episode being of moderate severity, as in F32.1, and without any history of mania.
F33.2Recurrent depressive disorder, current episode severe without psychotic symptoms
A disorder characterized by repeated episodes of depression, the current episode being severe without psychotic symptoms, as in F32.2, and without any history of mania. Endogenous depression without psychotic symptoms. Major depression, recurrent without psychotic symptomsManic-depressive psychosis, depressed type without psychotic symptoms viral depression, recurrent without psychotic symptoms
F33.3Recurrent depressive disorder, current episode severe with psychotic symptoms
A disorder characterized by repeated episodes of depression, the current episode being severe with psychotic symptoms, as in F32.3, and with no previous episodes of mania. Endogenous depression with psychotic symptomsManic-depressive psychosis, depressed type with psychotic symptoms recurrent severe episodes of:
- major depression with psychotic symptoms
- psychogenic depressive psychosis
- psychotic depression
- reactive depressive psychosis
F33.4Recurrent depressive disorder, currently in remission
The patient has had two or more depressive episodes as described in F33.0-F33.3, in the past, but has been free from depressive symptoms for several months.
F33.8Other recurrent depressive disorders
F33.9Recurrent depressive disorder, unspecified






SUICIDE PREVENTION
If you think someone is at immediate risk of self-harm or hurting another person:
- Call 911 or your local emergency number.
- Stay with the person until help arrives.
- Remove any guns, knives, medications, or other things that may cause harm.
- Listen, but don’t judge, argue, threaten, or yell.
- If you or someone you know is considering suicide, get help from a crisis or suicide prevention hotline. Try the National Suicide Prevention Lifeline at 800-273-8255.
Published: July 04, 2022
Last Updated: October 31, 2023


Published: November 14, 2023
How Long Does Postpartum Depression Last?
The journey into motherhood is often portrayed as a time of joy, but for some women, it can be marred by the relentless grip of postpartum depression (PPD). One common question that lingers in the minds of new mothers grappling with this condition is, “How long does postpartum depression last?” In this article, we aim […]
Read more

Published: November 14, 2023
Serotonin vs. Dopamine: What Are the Differences?
Serotonin and dopamine are two essential neurotransmitters that play distinct yet interconnected roles in our brain and body. Often referred to as the “feel-good” chemicals, they contribute to our mood, behavior, and overall well-being. In this article, we’ll delve into the differences between serotonin and dopamine, exploring their functions, effects, and how they impact our […]
Read more

Published: October 31, 2023
Navigating Mental Health Services in California: A Comprehensive Guide
Mental health is an essential aspect of overall well-being, and access to quality mental health services is crucial for individuals and communities. In California, a state known for its diversity and progressive policies, there is a wide range of mental health services available. This comprehensive guide will explore the landscape of mental health services in […]
Read more